2.1M XNAS Volume
XNAS 07 Apr, 2025 4:02 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 7,600 | 7,600 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 16,188 | 108,101 (0%) | 0% | 0 | Common Stock | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 16,188 | 137,251 (0%) | 0% | 0 | Common Stock | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 7,600 | 7,600 | - | - | Stock Option (right to buy) | |
| Christopher A. Van Tuyl | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 71,531 | 71,531 | - | - | Stock Option (right to buy) | |
| Christopher A. Van Tuyl | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 50,787 | 160,743 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 16,188 | 102,851 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 7,600 | 7,600 | - | - | Stock Option (right to buy) | |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 76,181 | 216,172 (0%) | 0% | 0 | Common Stock | |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 107,297 | 107,297 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 199,365 | 835,039 (1%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 93,599 | 93,599 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 7,600 | 7,600 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 16,188 | 135,773 (0%) | 0% | 0 | Common Stock | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 374,395 | 374,395 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 265,820 | 1,214,606 (2%) | 0% | 0 | Common Stock | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 125,180 | 125,180 | - | - | Stock Option (right to buy) | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 88,878 | 410,830 (0%) | 0% | 0 | Common Stock | |
| Michael Geffner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 143,063 | 143,063 | - | - | Stock Option (right to buy) | |
| Michael Geffner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 101,574 | 233,888 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Sale of securities on an exchange or to another person at price $ 19.52 per share. | 07 Mar 2025 | 6,616 | 93,297 (0%) | 0% | 19.5 | 129,144 | Common Stock |
| Andrew J. Fromkin | Director | Sale of securities on an exchange or to another person at price $ 19.96 per share. | 07 Mar 2025 | 1,384 | 91,913 (0%) | 0% | 20.0 | 27,625 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 20.86 per share. | 19 Feb 2025 | 15,439 | 948,786 (1%) | 0% | 20.9 | 322,058 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 20.86 per share. | 19 Feb 2025 | 2,055 | 357,353 (0%) | 0% | 20.9 | 42,867 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.86 per share. | 19 Feb 2025 | 2,814 | 321,952 (0%) | 0% | 20.9 | 58,700 | Common Stock |
| Jay S. Stout | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 23.59 per share. | 22 Jan 2025 | 2,195 | 139,991 (0%) | 0% | 23.6 | 51,780 | Common Stock |
| Michael Geffner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 23.59 per share. | 22 Jan 2025 | 2,657 | 132,314 (0%) | 0% | 23.6 | 62,679 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 23.81 per share. | 15 Jan 2025 | 8,352 | 964,640 (1%) | 0% | 23.8 | 198,861 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 24.19 per share. | 15 Jan 2025 | 415 | 964,225 (1%) | 0% | 24.2 | 10,039 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 24.21 per share. | 15 Jan 2025 | 19 | 359,408 (0%) | 0% | 24.2 | 460 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 24.19 per share. | 15 Jan 2025 | 94 | 359,814 (0%) | 0% | 24.2 | 2,274 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 23.81 per share. | 15 Jan 2025 | 387 | 359,427 (0%) | 0% | 23.8 | 9,214 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 23.81 per share. | 15 Jan 2025 | 1,883 | 359,908 (0%) | 0% | 23.8 | 44,834 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 24.19 per share. | 15 Jan 2025 | 109 | 324,766 (0%) | 0% | 24.2 | 2,637 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 23.81 per share. | 15 Jan 2025 | 2,189 | 324,875 (0%) | 0% | 23.8 | 52,120 | Common Stock |
| A. Christopher Van Tuyl | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 137,446 | 137,446 | - | - | Stock Option (right to buy) | |
| A. Van Tuyl Christopher | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 109,956 | 109,956 (0%) | 0% | 0 | Common Stock | |
| Pande Atul | Director | Sale of securities on an exchange or to another person at price $ 28.54 per share. | 02 Dec 2024 | 7,750 | 86,663 (0%) | 0% | 28.5 | 221,185 | Common Stock |
| J. Douglas Hughes | Director | Sale of securities on an exchange or to another person at price $ 28.54 per share. | 02 Dec 2024 | 5,425 | 119,585 (0%) | 0% | 28.5 | 154,830 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 25.45 per share. | 20 Nov 2024 | 3,650 | 319,228 (0%) | 0% | 25.5 | 92,893 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 25.45 per share. | 20 Nov 2024 | 16,692 | 978,097 (1%) | 0% | 25.4 | 424,811 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 25.45 per share. | 20 Nov 2024 | 3,353 | 361,791 (0%) | 0% | 25.5 | 85,334 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 25.45 per share. | 20 Nov 2024 | 4,174 | 331,169 (0%) | 0% | 25.4 | 106,228 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.53 per share. | 23 Oct 2024 | 4,361 | 322,878 (0%) | 0% | 29.5 | 128,780 | Common Stock |
| Jay S. Stout | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 29.53 per share. | 23 Oct 2024 | 2,740 | 142,186 (0%) | 0% | 29.5 | 80,912 | Common Stock |
| Michael Geffner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.53 per share. | 23 Oct 2024 | 3,189 | 134,971 (0%) | 0% | 29.5 | 94,171 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 28.79 per share. | 16 Oct 2024 | 2,860 | 327,239 (0%) | 0% | 28.8 | 82,339 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 28.79 per share. | 16 Oct 2024 | 9,095 | 994,789 (1%) | 0% | 28.8 | 261,845 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.79 per share. | 16 Oct 2024 | 2,627 | 365,705 (0%) | 0% | 28.8 | 75,631 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.79 per share. | 16 Oct 2024 | 561 | 365,144 (0%) | 0% | 28.8 | 16,151 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.79 per share. | 16 Oct 2024 | 3,271 | 335,343 (0%) | 0% | 28.8 | 94,172 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 29.56 per share. | 09 Oct 2024 | 4,460 | 1,003,884 (1%) | 0% | 29.6 | 131,838 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 29.56 per share. | 09 Oct 2024 | 5,162 | 338,614 (0%) | 0% | 29.6 | 152,589 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 31.84 per share. | 21 Aug 2024 | 3,164 | 330,230 (0%) | 0% | 31.8 | 100,742 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 32.32 per share. | 21 Aug 2024 | 131 | 330,099 (0%) | 0% | 32.3 | 4,234 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 31.84 per share. | 21 Aug 2024 | 2,907 | 441,079 (0%) | 0% | 31.8 | 92,559 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 32.32 per share. | 21 Aug 2024 | 120 | 440,959 (0%) | 0% | 32.3 | 3,878 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 32.32 per share. | 21 Aug 2024 | 598 | 1,008,344 (1%) | 0% | 32.3 | 19,327 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 31.84 per share. | 21 Aug 2024 | 14,470 | 1,008,942 (1%) | 0% | 31.8 | 460,725 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 32.32 per share. | 21 Aug 2024 | 120 | 368,332 (0%) | 0% | 32.3 | 3,878 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 31.84 per share. | 21 Aug 2024 | 2,907 | 368,452 (0%) | 0% | 31.8 | 92,559 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 32.32 per share. | 21 Aug 2024 | 149 | 343,776 (0%) | 0% | 32.3 | 4,816 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 31.84 per share. | 21 Aug 2024 | 3,619 | 343,925 (0%) | 0% | 31.8 | 115,229 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 27.76 per share. | 24 Jul 2024 | 4,015 | 333,394 (0%) | 0% | 27.8 | 111,456 | Common Stock |
| Jay S. Stout | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 27.76 per share. | 24 Jul 2024 | 2,813 | 144,926 (0%) | 0% | 27.8 | 78,089 | Common Stock |
| Michael Geffner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 27.76 per share. | 24 Jul 2024 | 3,456 | 138,160 (0%) | 0% | 27.8 | 95,939 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 2,358 | 337,556 (0%) | 0% | 29.6 | 69,891 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 147 | 337,409 (0%) | 0% | 30.6 | 4,491 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 2,698 | 444,155 (0%) | 0% | 29.6 | 79,969 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 169 | 443,986 (0%) | 0% | 30.6 | 5,163 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 8,175 | 1,023,922 (1%) | 0% | 29.6 | 242,307 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 510 | 1,023,412 (1%) | 0% | 30.6 | 15,581 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 31 | 371,359 (0%) | 0% | 30.5 | 947 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 504 | 371,390 (0%) | 0% | 29.6 | 14,939 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 147 | 371,894 (0%) | 0% | 30.6 | 4,491 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 2,362 | 372,041 (0%) | 0% | 29.6 | 70,010 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.55 per share. | 17 Jul 2024 | 184 | 347,544 (0%) | 0% | 30.5 | 5,621 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 29.64 per share. | 17 Jul 2024 | 2,939 | 347,728 (0%) | 0% | 29.6 | 87,112 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 28.06 per share. | 09 Jul 2024 | 1,527 | 446,853 (0%) | 0% | 28.1 | 42,848 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 28.06 per share. | 09 Jul 2024 | 4,619 | 1,032,097 (1%) | 0% | 28.1 | 129,609 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.06 per share. | 09 Jul 2024 | 4,747 | 350,667 (0%) | 0% | 28.1 | 133,201 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.65 per share. | 22 May 2024 | 3,242 | 339,914 (0%) | 0% | 29.6 | 96,125 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.65 per share. | 22 May 2024 | 3,247 | 448,380 (0%) | 0% | 29.7 | 96,274 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 29.65 per share. | 22 May 2024 | 16,163 | 1,036,716 (1%) | 0% | 29.7 | 479,233 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.65 per share. | 22 May 2024 | 3,247 | 374,403 (0%) | 0% | 29.7 | 96,274 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 29.65 per share. | 22 May 2024 | 4,042 | 355,414 (0%) | 0% | 29.6 | 119,845 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 28.90 per share. | 24 Apr 2024 | 3,963 | 343,156 (0%) | 0% | 28.9 | 114,531 | Common Stock |
| Jay S. Stout | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 28.90 per share. | 24 Apr 2024 | 7,239 | 147,739 (0%) | 0% | 28.9 | 209,207 | Common Stock |
| Michael Geffner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.90 per share. | 24 Apr 2024 | 3,261 | 141,616 (0%) | 0% | 28.9 | 94,243 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 7,602 | 349,344 (0%) | 0% | 28.8 | 218,938 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 2,225 | 347,119 (0%) | 0% | 29.9 | 66,617 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 7,825 | 453,917 (0%) | 0% | 28.8 | 225,360 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 2,290 | 451,627 (0%) | 0% | 29.9 | 68,563 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 26,365 | 1,060,593 (1%) | 0% | 28.8 | 759,312 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 7,714 | 1,052,879 (1%) | 0% | 29.9 | 230,957 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 6,136 | 379,794 (0%) | 0% | 28.8 | 176,717 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 79 | 377,650 (0%) | 0% | 29.9 | 2,365 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 269 | 377,729 (0%) | 0% | 28.8 | 7,747 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 1,796 | 377,998 (0%) | 0% | 29.9 | 53,772 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.80 per share. | 17 Apr 2024 | 9,479 | 362,230 (0%) | 0% | 28.8 | 272,995 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 29.94 per share. | 17 Apr 2024 | 2,774 | 359,456 (0%) | 0% | 29.9 | 83,054 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 31.18 per share. | 09 Apr 2024 | 1,053 | 461,742 (0%) | 0% | 31.2 | 32,833 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 31.18 per share. | 09 Apr 2024 | 4,807 | 1,086,958 (1%) | 0% | 31.2 | 149,882 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 31.18 per share. | 09 Apr 2024 | 3,689 | 371,709 (0%) | 0% | 31.2 | 115,023 | Common Stock |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 11,255 | 99,913 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 4,690 | 4,690 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 11,255 | 121,063 (0%) | 0% | 0 | Common Stock | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 4,690 | 4,690 | - | - | Stock Option (right to buy) | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 356,946 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 11,255 | 94,413 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 4,690 | 4,690 | - | - | Stock Option (right to buy) | |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 154,978 (0%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 50,167 | 50,167 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 120,400 | 635,674 (1%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 4,690 | 4,690 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 11,255 | 125,010 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 462,795 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 160,534 | 1,091,765 (1%) | 0% | 0 | Common Stock | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 200,667 | 200,667 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 385,930 (0%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 375,398 (0%) | 0% | 0 | Common Stock | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Michael Geffner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 54,978 | 144,877 (0%) | 0% | 0 | Common Stock | |
| Michael Geffner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Apr 2024 | 68,723 | 68,723 | - | - | Stock Option (right to buy) | |
| Renee Eva Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Feb 2024 | 2,930 | 320,420 (0%) | 0% | 36.2 | 105,920 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Feb 2024 | 2,221 | 330,952 (0%) | 0% | 36.1 | 80,289 | Common Stock |
| S. Levine Mark | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Feb 2024 | 2,134 | 301,968 (0%) | 0% | 36.1 | 77,144 | Common Stock |
| Butchko G. Julia | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Feb 2024 | 2,146 | 407,817 (0%) | 0% | 36.2 | 77,578 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 36.15 per share. | 22 Feb 2024 | 13,454 | 931,231 (1%) | 0% | 36.1 | 486,362 | Common Stock |
| S. Levine Mark | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 37.91 per share. | 26 Jan 2024 | 2,981 | 304,148 (0%) | 0% | 37.9 | 113,010 | Common Stock |
| S. Mark Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 38.46 per share. | 26 Jan 2024 | 46 | 304,102 (0%) | 0% | 38.5 | 1,769 | Common Stock |
| Geffner Michael | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 37.91 per share. | 26 Jan 2024 | 9,948 | 90,052 (0%) | 0% | 37.9 | 377,129 | Common Stock |
| Michael Geffner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 38.45 per share. | 26 Jan 2024 | 153 | 89,899 (0%) | 0% | 38.5 | 5,883 | Common Stock |
| William Macias L. | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 41.03 per share. | 18 Jan 2024 | 424 | 333,173 (0%) | 0% | 41.0 | 17,397 | Common Stock |
| Barnett Renee Eva | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 41.64 per share. | 11 Jan 2024 | 2,681 | 324,184 (0%) | 0% | 41.6 | 111,637 | Common Stock |
| Renee Eva Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 42.43 per share. | 11 Jan 2024 | 834 | 323,350 (0%) | 0% | 42.4 | 35,387 | Common Stock |
| Butchko Julia G. | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 38.59 per share. | 05 Jan 2024 | 1,297 | 409,963 (0%) | 0% | 38.6 | 50,051 | Common Stock |
| Salzmann Peter | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 38.59 per share. | 05 Jan 2024 | 3,824 | 944,685 (1%) | 0% | 38.6 | 147,568 | Common Stock |
| V. George Migausky | Director | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 01 Dec 2023 | 4,200 | 118,308 (0%) | 0% | 38.8 | 162,918 | Common Stock |
| Pande Atul | Director | Sale of securities on an exchange or to another person at price $ 38.80 per share. | 01 Dec 2023 | 4,129 | 91,379 (0%) | 0% | 38.8 | 160,205 | Common Stock |
| Andrew J. Fromkin | Director | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 01 Dec 2023 | 4,773 | 88,658 (0%) | 0% | 40.5 | 193,116 | Common Stock |
| Fromkin J. Andrew | Director | Sale of securities on an exchange or to another person at price $ 38.78 per share. | 01 Dec 2023 | 3,941 | 97,067 (0%) | 0% | 38.8 | 152,832 | Common Stock |
| V. George Migausky | Director | Sale of securities on an exchange or to another person at price $ 39.81 per share. | 01 Dec 2023 | 3,478 | 114,830 (0%) | 0% | 39.8 | 138,459 | Common Stock |
| Atul Pande | Director | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 01 Dec 2023 | 4,847 | 83,158 (0%) | 0% | 40.5 | 196,110 | Common Stock |
| Fromkin J. Andrew | Director | Sale of securities on an exchange or to another person at price $ 39.81 per share. | 01 Dec 2023 | 3,636 | 93,431 (0%) | 0% | 39.8 | 144,749 | Common Stock |
| Pande Atul | Director | Sale of securities on an exchange or to another person at price $ 39.82 per share. | 01 Dec 2023 | 3,374 | 88,005 (0%) | 0% | 39.8 | 134,353 | Common Stock |
| V. George Migausky | Director | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 01 Dec 2023 | 5,022 | 109,808 (0%) | 0% | 40.5 | 203,190 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 22.48 per share. | 30 Aug 2023 | 5,908 | 969,965 (1%) | 0% | 22.5 | 132,812 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 21.97 per share. | 30 Aug 2023 | 50,866 | 975,873 (1%) | 0% | 22.0 | 1,117,526 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 21.00 per share. | 24 Aug 2023 | 1 | 314,488 (0%) | 0% | 21 | 21 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 24 Aug 2023 | 12,285 | 314,489 (0%) | 0% | 20.3 | 249,386 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 21.00 per share. | 24 Aug 2023 | 1 | 416,260 (0%) | 0% | 21 | 21 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 24 Aug 2023 | 12,332 | 416,261 (0%) | 0% | 20.3 | 250,340 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 24 Aug 2023 | 12,332 | 337,393 (0%) | 0% | 20.3 | 250,340 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 21.00 per share. | 24 Aug 2023 | 1 | 337,392 (0%) | 0% | 21 | 21 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.00 per share. | 24 Aug 2023 | 1 | 335,477 (0%) | 0% | 21 | 21 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 24 Aug 2023 | 14,385 | 335,478 (0%) | 0% | 20.3 | 292,016 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 22.04 per share. | 14 Aug 2023 | 11,314 | 1,026,739 (1%) | 0% | 22.0 | 249,361 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 21.34 per share. | 14 Aug 2023 | 91,744 | 1,038,053 (1%) | 0% | 21.3 | 1,957,817 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 21.73 per share. | 07 Aug 2023 | 101,339 | 1,129,797 (2%) | 0% | 21.7 | 2,202,096 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 21.63 per share. | 26 Jul 2023 | 3,917 | 326,774 (0%) | 0% | 21.6 | 84,725 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 24.94 per share. | 19 Jul 2023 | 426 | 349,725 (0%) | 0% | 24.9 | 10,624 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 24.94 per share. | 19 Jul 2023 | 2,725 | 349,863 (0%) | 0% | 24.9 | 67,962 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 19.73 per share. | 12 Jul 2023 | 1,470 | 428,593 (0%) | 0% | 19.7 | 29,003 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 19.73 per share. | 12 Jul 2023 | 3,233 | 1,231,136 (2%) | 0% | 19.7 | 63,787 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 16.29 per share. | 25 Apr 2023 | 2,633 | 330,691 (0%) | 0% | 16.3 | 42,892 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 16.29 per share. | 25 Apr 2023 | 509 | 350,151 (0%) | 0% | 16.3 | 8,292 | Common Stock |
| Julia G. Butchko | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 15.27 per share. | 18 Apr 2023 | 1,544 | 430,063 (0%) | 0% | 15.3 | 23,577 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 15.27 per share. | 18 Apr 2023 | 3,395 | 1,234,369 (2%) | 0% | 15.3 | 51,842 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 15.27 per share. | 18 Apr 2023 | 3,423 | 352,588 (0%) | 0% | 15.3 | 52,269 | Common Stock |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2023 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Jay S. Stout | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2023 | 100,000 | 100,000 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 12,523 | 101,008 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 16,260 | 16,260 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 16,260 | 16,260 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 12,523 | 122,508 (0%) | 0% | 0 | Common Stock | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 113,821 | 113,821 | - | - | Stock Option (right to buy) | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 87,664 | 333,324 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 12,523 | 95,508 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 16,260 | 16,260 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 158,292 | 158,292 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 121,916 | 515,274 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 16,260 | 16,260 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 12,523 | 113,755 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 100,188 | 431,607 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 130,081 | 130,081 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 316,585 | 316,585 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 243,832 | 1,237,764 (2%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 113,821 | 113,821 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 87,664 | 350,660 (0%) | 0% | 0 | Common Stock | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 113,821 | 113,821 | - | - | Stock Option (right to buy) | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Apr 2023 | 87,664 | 356,011 (0%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 18.24 per share. | 02 Feb 2023 | 537 | 262,996 (0%) | 0% | 18.2 | 9,795 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 18.51 per share. | 26 Jan 2023 | 10,156 | 245,660 (0%) | 0% | 18.5 | 187,988 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 15.16 per share. | 11 Jan 2023 | 19 | 391,890 (0%) | 0% | 15.2 | 288 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 16.79 per share. | 11 Jan 2023 | 60,471 | 331,419 (0%) | 0% | 16.8 | 1,015,308 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 16.80 per share. | 11 Jan 2023 | 4,021 | 993,932 (1%) | 0% | 16.8 | 67,553 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 16.75 per share. | 11 Jan 2023 | 44,448 | 263,533 (0%) | 0% | 16.8 | 744,504 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 15.11 per share. | 11 Jan 2023 | 120 | 307,981 (0%) | 0% | 15.1 | 1,813 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 15.18 per share. | 11 Jan 2023 | 11 | 272,846 (0%) | 0% | 15.2 | 167 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 16.75 per share. | 11 Jan 2023 | 4,499 | 268,347 (0%) | 0% | 16.7 | 75,358 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 9.67 per share. | 21 Oct 2022 | 341 | 308,101 (0%) | 0% | 9.7 | 3,297 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 9.18 per share. | 13 Oct 2022 | 928 | 391,909 (0%) | 0% | 9.2 | 8,519 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 9.18 per share. | 13 Oct 2022 | 2,793 | 997,953 (1%) | 0% | 9.2 | 25,640 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 9.44 per share. | 11 Oct 2022 | 12,500 | 272,857 (0%) | 0% | 9.4 | 118,000 | Common Stock |
| Atul Pande | Director | Purchase of securities on an exchange or from another person at price $ 5.60 per share. | 30 Sep 2022 | 15,000 | 20,000 (0%) | 0% | 5.6 | 84,000 | Common Stock |
| Frank M. Torti | Director | Purchase of securities on an exchange or from another person at price $ 5.81 per share. | 29 Sep 2022 | 20,000 | 393,358 (0%) | 0% | 5.8 | 116,200 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 4.67 per share. | 28 Sep 2022 | 535 | 392,837 (0%) | 0% | 4.7 | 2,498 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 4.67 per share. | 28 Sep 2022 | 1,605 | 1,000,746 (1%) | 0% | 4.7 | 7,495 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 5.83 per share. | 30 Aug 2022 | 548 | 393,372 (0%) | 0% | 5.8 | 3,195 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 5.83 per share. | 30 Aug 2022 | 1,644 | 1,002,351 (1%) | 0% | 5.8 | 9,585 | Common Stock |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 31,668 | 31,668 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 21,059 | 88,485 (0%) | 0% | 0 | Common Stock | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 31,668 | 31,668 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 21,059 | 109,985 (0%) | 0% | 0 | Common Stock | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 112,816 | 255,816 (0%) | 0% | 0 | Common Stock | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 169,648 | 169,648 | - | - | Stock Option (right to buy) | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 31,668 | 31,668 | - | - | Stock Option (right to buy) | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 21,059 | 82,985 (0%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 339,296 | 339,296 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 225,632 | 373,358 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 21,059 | 101,232 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 31,668 | 31,668 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 112,816 | 393,920 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 169,648 | 169,648 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 451,264 | 1,003,995 (1%) | 0% | 0 | Common Stock | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 678,592 | 678,592 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 112,816 | 308,442 (0%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 169,648 | 169,648 | - | - | Stock Option (right to buy) | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 169,648 | 169,648 | - | - | Stock Option (right to buy) | |
| Eva Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2022 | 112,816 | 285,357 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 4.27 per share. | 27 Jul 2022 | 510 | 281,104 (0%) | 0% | 4.3 | 2,178 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 4.27 per share. | 27 Jul 2022 | 1,528 | 552,731 (0%) | 0% | 4.3 | 6,525 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 4.70 per share. | 22 Jul 2022 | 322 | 195,626 (0%) | 0% | 4.7 | 1,513 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 4.02 per share. | 29 Jun 2022 | 460 | 281,614 (0%) | 0% | 4.0 | 1,849 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 4.02 per share. | 29 Jun 2022 | 1,376 | 554,259 (0%) | 0% | 4.0 | 5,532 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 3.79 per share. | 24 May 2022 | 492 | 282,074 (0%) | 0% | 3.8 | 1,865 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 3.79 per share. | 24 May 2022 | 1,471 | 555,635 (0%) | 0% | 3.8 | 5,575 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 4.72 per share. | 27 Apr 2022 | 541 | 282,566 (0%) | 0% | 4.7 | 2,554 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 4.72 per share. | 27 Apr 2022 | 1,622 | 557,106 (0%) | 0% | 4.7 | 7,656 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 4.98 per share. | 19 Apr 2022 | 1,392 | 195,948 (0%) | 0% | 5.0 | 6,932 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 5.90 per share. | 24 Mar 2022 | 6,381 | 283,107 (0%) | 0% | 5.9 | 37,648 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 5.90 per share. | 24 Mar 2022 | 19,227 | 558,728 (0%) | 0% | 5.9 | 113,439 | Common Stock |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2022 | 143,000 | 143,000 (0%) | 0% | 0 | Common Stock | |
| Mark S. Levine | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2022 | 383,000 | 383,000 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 21,726 | 67,426 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 71,492 | 208,973 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 71,492 | 131,792 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 21,726 | 88,926 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 71,492 | 208,973 | - | - | Stock Option (right to buy) | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 21,726 | 61,926 (0%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 329,485 | 554,748 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 100,126 | 147,726 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 21,726 | 80,173 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2022 | 71,492 | 208,973 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale of securities on an exchange or to another person at price $ 7.25 per share. | 07 Jan 2022 | 55,318 | 289,488 (0%) | 0% | 7.3 | 401,056 | Common Stock |
| Peter Salzmann | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 7.25 per share. | 07 Jan 2022 | 125,158 | 577,955 (1%) | 0% | 7.3 | 907,396 | Common Stock |
| Eva Renee Barnett | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.25 per share. | 07 Jan 2022 | 29,959 | 172,541 (0%) | 0% | 7.3 | 217,203 | Common Stock |
| William L. Macias | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 8.28 per share. | 05 Jan 2022 | 26,813 | 197,340 (0%) | 0% | 8.3 | 222,012 | Common Stock |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 167,325 | 167,325 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 112,108 | 224,153 (0%) | 0% | 0 | Common Stock | |
| Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Oct 2021 | 333,000 | 333,000 | - | - | Stock Option (right to buy) | |
| Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Oct 2021 | 143,000 | 202,500 (0%) | 0% | 0 | Common Stock | |
| Renee Barnett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Oct 2021 | 59,500 | 59,500 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 11 Sep 2021 | 191,100 | 0 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2021 | 319,700 | 319,700 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 11 Sep 2021 | 319,700 | 0 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2021 | 191,100 | 191,100 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2021 | 430,700 | 430,700 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2021 | 464,700 | 464,700 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 11 Sep 2021 | 430,700 | 0 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 11 Sep 2021 | 464,700 | 0 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2021 | 369,320 | 369,320 | - | - | Stock Option (right to buy) | |
| William L. Macias | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 11 Sep 2021 | 369,320 | 0 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Purchase of securities on an exchange or from another person at price $ 8.24 per share. | 27 Aug 2021 | 18,247 | 58,447 (0%) | 0% | 8.2 | 150,355 | Common Stock |
| George V. Migausky | Director | Purchase of securities on an exchange or from another person at price $ 7.65 per share. | 20 Aug 2021 | 7,000 | 67,200 (0%) | 0% | 7.7 | 53,550 | Common Stock |
| Atul Pande | Director | Purchase of securities on an exchange or from another person at price $ 7.98 per share. | 13 Aug 2021 | 5,000 | 45,200 (0%) | 0% | 8.0 | 39,900 | Common Stock |
| Andrew J. Fromkin | Director | Purchase of securities on an exchange or from another person at price $ 7.90 per share. | 10 Aug 2021 | 5,500 | 45,700 (0%) | 0% | 7.9 | 43,450 | Common Stock |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 285,306 | 344,806 (0%) | 0% | 0 | Common Stock | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 570,613 | 703,113 (1%) | 1% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 18,674 | 18,674 (0%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 93,371 | 112,045 (0%) | 0% | 0 | Common Stock | |
| William L. Macias | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 369,320 | 369,320 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 15,500 | 40,200 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 23,300 | 23,300 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 23,300 | 23,300 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 15,500 | 60,200 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 15,500 | 40,200 (0%) | 0% | 0 | Common Stock | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 23,300 | 23,300 | - | - | Stock Option (right to buy) | |
| Rita I. Jain | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 342,300 | 342,300 | - | - | Stock Option (right to buy) | |
| Rita I. Jain | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 97,600 | 117,600 (0%) | 0% | 0 | Common Stock | |
| Rita I. Jain | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 11,765 | 129,365 (0%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 19,200 | 47,600 (0%) | 0% | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 28,900 | 28,900 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 15,500 | 40,200 (0%) | 0% | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 23,300 | 23,300 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 54,500 | 59,500 (0%) | 0% | 0 | Common Stock | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 191,100 | 191,100 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 132,500 | 132,500 (0%) | 0% | 0 | Common Stock | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 464,700 | 464,700 | - | - | Stock Option (right to buy) | |
| Pamela Yanchik Connealy | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 46,200 | 46,200 (0%) | 0% | 0 | Common Stock | |
| Pamela Yanchik Connealy | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 162,000 | 162,000 | - | - | Stock Option (right to buy) | |
| Michael James Elliott | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 97,600 | 97,600 (0%) | 0% | 0 | Common Stock | |
| Michael James Elliott | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2021 | 342,300 | 342,300 | - | - | Stock Option (right to buy) | |
| Rita I. Jain | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jan 2021 | 20,000 | 20,000 (0%) | 0% | 0 | Common Stock | |
| Rita I. Jain | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jan 2021 | 220,000 | 220,000 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Purchase of securities on an exchange or from another person at price $ 38.17 per share. | 11 Sep 2020 | 5,000 | 5,000 (0%) | 0% | 38.2 | 190,850 | Common Stock |
| Michael James Elliott | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Sep 2020 | 400,000 | 400,000 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 37,000 | 37,000 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 24,700 | 24,700 (0%) | - | 0 | Common Stock | |
| W. Bradford Middlekauff | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 142,600 | 142,600 | - | - | Stock Option (right to buy) | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 24,700 | 24,700 (0%) | - | 0 | Common Stock | |
| George V. Migausky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 37,000 | 37,000 | - | - | Stock Option (right to buy) | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 37,000 | 37,000 | - | - | Stock Option (right to buy) | |
| Atul Pande | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 24,700 | 24,700 (0%) | - | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 28,400 | 28,400 (0%) | - | 0 | Common Stock | |
| Frank M. Torti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 42,600 | 42,600 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 24,700 | 24,700 (0%) | - | 0 | Common Stock | |
| Douglas J. Hughes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 37,000 | 37,000 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 319,700 | 319,700 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 430,700 | 430,700 | - | - | Stock Option (right to buy) | |
| Pamela Yanchik Connealy | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 180,500 | 180,500 | - | - | Stock Option (right to buy) | |
| Andrew J. Fromkin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 77,181 | 77,181 | - | - | Stock Option (right to buy) | |
| Myrtle S. Potter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 137,617 | 137,617 | - | - | Stock Option (right to buy) | |
| Myrtle S. Potter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 893 | 893 | - | - | Stock Option (right to buy) | |
| Myrtle S. Potter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 11,488 | 11,488 | - | - | Stock Option (right to buy) | |
| Myrtle S. Potter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 3,765 | 3,765 | - | - | Stock Option (right to buy) | |
| W. Bradford Middlekauff | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 489 | 489 | - | - | Stock Option (right to buy) | |
| W. Bradford Middlekauff | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 211,277 | 211,277 | - | - | Stock Option (right to buy) | |
| Atul Pande | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 77,181 | 77,181 | - | - | Stock Option (right to buy) | |
| Robert K. Zeldin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 380,325 | 380,325 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 137,617 | 137,617 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 893 | 893 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 11,488 | 11,488 | - | - | Stock Option (right to buy) | |
| Frank M. Torti | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 3,765 | 3,765 | - | - | Stock Option (right to buy) | |
| Douglas J. Hughes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 77,181 | 77,181 | - | - | Stock Option (right to buy) | |
| Julia G. Butchko | Chief Dev. & Tech. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 433,588 | 433,588 | - | - | Stock Option (right to buy) | |
| Peter Salzmann | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 1,479,043 | 1,479,043 | - | - | Stock Option (right to buy) | |
| Pamela Connealy Yanchik | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 433,588 | 433,588 | - | - | Stock Option (right to buy) | |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.92 per share. | 11 Dec 2019 | 31,500 | 902,498 (6%) | 0% | 10.9 | 344,024 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.38 per share. | 10 Dec 2019 | 25,971 | 870,998 (6%) | 0% | 10.4 | 269,517 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.20 per share. | 09 Dec 2019 | 50,000 | 845,027 (5%) | 0% | 10.2 | 510,125 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.25 per share. | 06 Dec 2019 | 400,000 | 795,027 (5%) | 2% | 10.3 | 4,100,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.15 per share. | 05 Dec 2019 | 20,000 | 395,027 (2%) | 0% | 10.2 | 203,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.15 per share. | 04 Dec 2019 | 20,000 | 375,027 (2%) | 0% | 10.2 | 203,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.45 per share. | 29 Nov 2019 | 26,918 | 315,027 (2%) | 0% | 10.4 | 281,293 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.21 per share. | 29 Nov 2019 | 20,000 | 355,027 (2%) | 0% | 10.2 | 204,200 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.40 per share. | 29 Nov 2019 | 20,000 | 335,027 (2%) | 0% | 10.4 | 208,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.49 per share. | 25 Nov 2019 | 4,000 | 284,109 (1%) | 0% | 10.5 | 41,960 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.48 per share. | 25 Nov 2019 | 4,000 | 288,109 (2%) | 0% | 10.5 | 41,904 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.50 per share. | 25 Nov 2019 | 4,000 | 280,109 (1%) | 0% | 10.5 | 42,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.42 per share. | 20 Nov 2019 | 15,194 | 274,109 (1%) | 0% | 10.4 | 158,299 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.54 per share. | 20 Nov 2019 | 2,000 | 276,109 (1%) | 0% | 10.5 | 21,080 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.39 per share. | 20 Nov 2019 | 29,805 | 258,915 (1%) | 0% | 10.4 | 309,582 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.25 per share. | 15 Nov 2019 | 29,805 | 199,305 (1%) | 0% | 10.2 | 305,501 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.25 per share. | 15 Nov 2019 | 29,805 | 229,110 (1%) | 0% | 10.2 | 305,501 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.29 per share. | 15 Nov 2019 | 13,000 | 169,500 (1%) | 0% | 10.3 | 133,800 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.17 per share. | 12 Nov 2019 | 13,000 | 143,500 (0%) | 0% | 10.2 | 132,210 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.17 per share. | 12 Nov 2019 | 13,000 | 156,500 (1%) | 0% | 10.2 | 132,210 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.17 per share. | 12 Nov 2019 | 100,000 | 130,500 (0%) | 0% | 10.2 | 1,017,000 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.18 per share. | 07 Nov 2019 | 13,000 | 30,500 (0%) | 0% | 10.2 | 132,340 | Common Shares |
| Roderick Wong | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.18 per share. | 07 Nov 2019 | 17,500 | 17,500 (0%) | 0% | 10.2 | 178,150 | Common Shares |